Differential Gene Expression Analysis


DGE involves the measurement of genes whose expression differ according to phenotype or experimental conditions. Some DGE analysis will not only measure variation but also the dependencies between genes. This requires the statistical analysis of large numbers of genes, isoforms and alternative splicing events. Current methods to analyze RNA-Seq data include those that quantify expression within the boundaries of previously published genes and methods developed to reconstruct full-length transcripts.

Providers offering Differential Gene Expression Analysis (found 46)


Kovid BioAnalytics Pvt. Ltd.

India

Kovid BioAnalytics is an Informatics and Analytics company based in India. We specialize in building software, web-based or standalone applications for various bioinformatics projects, data curation and analysis services, etc. With a team of Bioinformatics experts and Software Developers we provide the following services: 1) Bioinformatics Software Development 2) Website Design and Maintenance for Bioinformatics Services 3) Curation of Genomics/Proteomics Data 4) Manual annotation of bioinformatics data and data mining 5) Technical writing services 6) Significance Analysis of micro-array data

Years in service: 11

Other services offered by Kovid BioAnalytics Pvt. Ltd.:

Service Description Price
Differential Gene Expression Analysis We have experience in performing Differential Gene Expression Analysis for various researchers from institutes like Washington University at St. Louis, West Mead Hospital (Australia), Spain Cancer Center and Bar Ilan University (Israel), etc. $16.57 USD (per hour)
Other Services We have a team of 5 experienced Bioinformatics Experts and 2 web developers, that can built custom pipelines for NGS data analysis, web applications, data mining tools, websites, etc. $16.57 USD (per hour)
ChIP-Seq Analysis $20.00 USD (per hour)
Metagenomic Analysis We provide Metagenomic Analysis services including data curation as well as analysis. $15.57 USD (per hour)
Genome Annotation $15.00 USD (per hour)
Variant Annotation We provide variant annotation services that include manual annotation of variants using public databases as well as annotation through automated pipelines/tools like GEMINI. $16.57 USD (per hour)

Parseq Lab

Czechia

Parseq Lab is experienced in: - massively parallel sequencing data analysis - client-tailored algorithms and software development - analysis pipelines deployment

We offer: - whole genome/exome and targeted sequencing data analysis - de novo assembly - SGV detection and annotation - expression analyses - metagenomics analysis - transcriptomics analysis - proteomics research - genuine task-specific workflows design - custom bioinformatics applications development - statistical data analysis

Collaborations: genomic research labs, sequencing facilities, academic and research institutions.

Years in service: 13

Other services offered by Parseq Lab:

Service Description Price

ClickSeq Technologies

NGS provider United States of America

ClickSeq is a unique method for RNAseq and DNAseq that uses ‘Click-Chemistry’ in place of commonly used biological reagents such as fragmentases and ligases. ClickSeq is a very simple procedure and considerably cheaper than other commonly used alternatives.

No Fragmentation; No ligation; Highly scalable; Ultra-low artifactual chimera formation; Specialized Transcriptomic applications; Integrated analysis pipelines, from RNA to results; RNA or DNA Suitable for fragmented/degraded samples

Poly(A)-ClickSeq is a specialized technology in transcriptomics for sensitively, robustly and cheaply characterizing gene expression as well as poly(A) site positions. Poly(A)-ClickSeq only requires >100ng Total Cellular RNA (no rRNA depletion or poly(A) enrichment required) and by focusing just on the 3′ ends of mRNAs substantially reduces the amount of sequencing data required to obtain robust results.

Years in service: 5

Other services offered by ClickSeq Technologies:

Service Description Price
Differential Gene Expression Analysis Routine transcriptomics analyses for gene expression and differential gene expression analysis. 3'end targeted gene expression analysis and alternative polyadenylation analyses. $100.00 USD (per sample)
Transcriptome Mapping Routine transcriptomics analyses for gene expression and differential gene expression analysis. 3'end targeted gene expression analysis and alternative polyadenylation analyses. $100.00 USD (per sample)

Insightomics

Portugal

At Insightomics we specialize in bioinformatics data analysis services. Our team is able to deliver state-of-the-art bioinformatics methodologies to support Life Sciences R&D involving clinical and omics data.

We have experience working with human data and bacterial (S. pneumoniae) data.

Other services offered by Insightomics:

Service Description Price
Differential Gene Expression Analysis Contact us to discuss your specific project or data analysis needs. Inquire
Custom scripting and special projects Contact us to discuss your specific project or data analysis needs. Consult with our bioinformatics software development experts and data scientists. Inquire
Other Services Exploratory data analysis. Graphical techniques to uncover the data structure and gain insights. Let the data speak for itself. Inquire
Other Services Machine learning – Supervised learning. Machine learning models for discriminating data, for instance logistic regression, K-nearest neighbors, Support Vector Machines. Inquire
Other Services Deep learning. Apply state-of-the-art neural network methodologies in multiple bioinformatics contexts. Inquire
Other Services Bioinformatics pipeline alignment. Choose the most appropriate data analysis pipeline. Inquire
Other Services Machine learning – Unsupervised learning. Models for clustering data, for instance K-means, hierarchical clustering, mixture models. Inquire
Other Services Scientific Consulting. Advisory on statistical and machine learning methods applied to specific research goals in the life sciences. Technology alignment. Inquire
Other Services Dimensionality reduction. Feature selection and mapping of data to a lower dimensionality. Principal Component Analysis (PCA), multidimensional scaling. Inquire
Other Services Rapid BioApp Delivery. Development of new bioinformatics apps, accelerated by Insightomics Platform and powered by Insightomics Rapid BioApp Delivery methodology. Inquire
Other Services Principal Component Analysis (PCA) $250.00 USD (flat price)
Other Services Network and pathway analysis. Statistical overrepresentation testing. Gene set enrichment analysis. Molecular and genetic interaction graph analysis and visualization. Inquire
Other Services Probabilistic Bayesian modelling. State-of-the-art robust modelling for specific bioinformatics problems. Inquire
Other Services Other Services. Contact us to discuss your specific project or data analysis needs. Inquire
Other Services Data validation and preprocessing. Quality control, missing value imputation, data transformation and normalization. Inquire
Other Services Admixture modelling and phylogenetics. Infer the structure and evolutionary history of populations from genetic data. Inquire
Other Services Statistical hypothesis testing. Parametric and nonparametric tests applicable in a wide variety of contexts. Multiple hypothesis testing (Bonferroni correction, false discovery rate). Inquire
Other Services Survival analysis. Analyse censored time-to-event data with tools such as Cox regression and log-rank testing. Inquire

Quick Biology Inc.

NGS provider United States of America

Quick Biology Inc. is a CLIA-certified startup biotechnology company located in Monrovia, CA. QB has a fully automated, high-throughput genomic center equipped with all major next-generation sequencing. QB provides state-of-the-art genomics technologies, comprehensive services, and specialized expertise to enable our services in a cost-effective and timely manner to serve basic science and translational/clinical research.

We also help physicians to unleash the power of NGS in disease diagnosis. (U.S. Federal CLIA#: 05D2286116; California State CLIA ID: CLF-90009922)

★We are equipped with the latest Illumina NovaSeq X Plus, NovaSeq 6000, HiSeq X Ten, HiSeq 4000, NextSeq500, MiSeq and Ion Proton.

We have --High sequencing throughput and capacity (NovaSeq 6000 S2 flow cell, ~3300M reads of PE150) --Fast turnaround time (our NovaSeq runs once a week and Hiseq X runs twice a week on a routine basis) --Very competitive price in RNA-seq and Whole Exome Seq --Advanced bioinformatic analysis, including analysis for RNA splicing/RNA editing -- High-quality pictures for publication purposes

★We also provide functional genomic screening service using our proprietary Drug Array and siRNA Array to conduct functional studies on your pathway of interest through drug-drug and drug-gene interactions on your cell line of interest. (1) Drug Array: - This Drug Array comprises 66 highly selective anti-cancer drugs, which allows users to quickly screen potential drug-drug and drug-gene interactions. It serves as a great tool to survey synthetic lethality for cancer treatment. It also serves as a tool to probe pathway-pathway interactions. (2) siRNA Array - siRNA array for Drug Targets: This array set silences 60 well-known drug targets, which allows users to screen potential gene-gene and gene-drug interaction. - siRNA array for Cancer Driver Genes: This array set silences 60 well-known cancer driver genes.

Years in service: 9

Other services offered by Quick Biology Inc.:

Service Description Price
Differential Gene Expression Analysis $100.00 USD (per sample)
Exome Analysis Whole Exome Sequencing analysis: a.Germline variants, compared to reference genome b.Somatic mutations if Tumor-Normal pair (SNVs, InDel, CNV) c. Pathway Analysis of Variants d. Interaction Network Analysis of Variants $170.00 USD (per sample)
ChIP-Seq Analysis ChIP Sequencing analysis: a.Raw data QC and clean up b.Alignment to a reference with mapping statistics c.Peaking calling with or without control samples d.Gene assignment and peak annotation e.Visualization f.Final project report with analysis methods, publication-ready graphics, and references 120.00

Admera Health Biopharma Services

NGS provider United States of America

Admera Health is an advanced molecular diagnostics and research service provider. Utilizing genomic and proteomic technology platforms (such as next generation sequencing and aptamer), together with advanced bioinformatics, Biopharma Services of Admera Health seeks to redefine the delivery of transformative, valuable solutions for all researchers and biopharma companies.

Biopharma Services of Admera Health operates in a CLIA-certified and CAP-accredited laboratory for the development, validation, and delivery of proprietary laboratory developed tests (LDTs) as well as RUO (Research Use Only) services. We are committed to maintaining compliance with all clinical regulations and to upholding the highest quality standards for all our projects.

Please follow the link for more information: https://www.admerahealth.com/genomics-and-bioinformatics-2/

Years in service: 12

Other services offered by Admera Health Biopharma Services:

Service Description Price
Differential Gene Expression Analysis We provide full bioinformatics service from experimental design to RNA-Seq data analysis and statistical modeling, as well as GO/Pathway enrichment analysis Starting at $50 $50.00 USD (per sample)
Exome Analysis Our bioinformatics pipeline supports standard analysis from raw data quality assessment to variant annotation and any further customized analysis Starting at $75 $75.00 USD (per sample)
ChIP-Seq Analysis Our robust ChIP-Seq analysis pipeline includes raw data QC and clean up, reads mapping, differential binding analysis, peak calling and annotation, motif analysis, GO/pathway enrichment analysis $75.00 USD (per sample)

BioInfoRx

United States of America

At BioInfoRx, we help scientists obtain biological insights from complex genomic data. We provide complete NGS analytic solutions including standard analysis of raw data, integration between multiple experiments, and online database for data mining and visualizations. We use best-practice open source tools to analyze your raw NGS data, and provide meaningful annotations and downstream data mining tools to help you infer functional insights.

As demonstrated by the numerous publications using our services or web-bases tools, our biology-centric approach has proven effective to decipher molecular mechanisms from genomic data.

Years in service: 14

Other services offered by BioInfoRx:

Service Description Price
Differential Gene Expression Analysis We use a robust pipeline with flexible statistical models to identify differentially expressed genes (DEG) from raw RNA-Seq data. The list of DEG is only part of the results we delivery. We also help you assess data quality and verify your experimental design, and deliver your data in an online database where you can perform additional data mining: 1) Adjust filter criterion for DEG 2) Search f… $99.00 USD (per sample)
Custom scripting and special projects We offer a variety of custom genomic analysis services. Our team has both strong biological and computational background, and we can tackle any questions for you. -Custom genome browser -Online genomic database -Circo plots, pathway analysis -Functional annotation of newly sequences genomes -Integrative analysis of RNA-Seq, ChIP-Seq, motif discovery, etc. $125.00 USD (per hour)
Exome Analysis We use best-practice method to map reads and make variant calls. We include robust quality control metrics for exome capture performance. The variants come with rich annotation regarding effects on genes and regulatory regions. $99.00 USD (per sample)
ChIP-Seq Analysis Finally you can unleash the full potential of your ChIP-Seq data in a quick and easy way. With the biologist-friendly web interface powered by BxChIPSeq 2.0, you can focus on the biology without worrying about hardware, software, algorithms. -Peak Report (with gene annotations, and enriched genomic regions) -De novo motif discovery, and enriched known motifs -Functional enrichment of genes (G… $99.00 USD (per sample)
Targeted Capture Analysis We use best-practice method to map reads and make variant calls. We include robust quality control metrics for target capture performance. The variants come with rich annotation regarding effects on genes and regulatory regions. $99.00 USD (per sample)

Igenbio, Inc.

United States of America

Expertise:

Igenbio, Inc. develops genome analysis products and services for the life science industry. Our scientists have broad experience in both in silico and wet lab sequencing, research and development with more than 100 relevant publications in these areas. Igenbio has a proven track record of delivering scientific results for academic, governmental, and industrial institutions for two decades.

Our expertise includes, but is not limited to:

  • Whole Genome Sequencing
  • RNA-Sequencing
  • Metatranscriptomics Sequencing
  • Metagenome Sequencing
  • Common and custom amplicon sequencing
  • Genome Assembly & Annotation
  • RNA-Seq Analysis
  • Amplicon Sequencing Analysis
  • Metagenome Analysis
  • Genome ORF calling: Eukaryotes and Prokaryote Genomes
  • Pathway Analysis
  • Metabolic Reconstruction
  • SNP Discovery & Analysis
  • Comparative Genomics
  • Available for all organisms, including humans, animals, plants, bacteria, and viruses.
  • Haploid, diploid or polyploid assemblies

Infrastructure:

Igenbio has a large, secure cloud infrastructure that can expand to meet any project demands you may have - from large number of samples to quick turnaround times. Please inquire for more information.

At Igenbio, Inc. security of your data is a top priority. Your data is protected by best practices in physical and data security measures. This includes 24/7 physical security and monitoring, and the best available encryption for storage and transmission. Our employees are trained and knowledgeable in data security best practices.

Years in service: 11

Other services offered by Igenbio, Inc.:

Service Description Price
Differential Gene Expression Analysis Inquire
Comparative Genome Analysis Inquire
Metagenomic Analysis - Quality analytics of sequence reads - State of the art sample processing using academically-proven tools such as DADA2 and Kraken2 that work on all sequencing platforms such as Illumina & Pacific Biosciences. - Fast and accurate taxa identification using state-of-the-art machine learning algorithms that can identify taxa down to the species level. - Supports public databases (such as Silva,… Inquire
SNP / Indel Calling Inquire
SNP/SV/CNV Discovery Inquire
Genome Annotation Gene Annotation and Functional Assignments placing genes into their functional or metabolic context utilizing KEGG Pathways, Gene Ontology, and the ERGO database. Optional - Identification of Antibiotic Resistance - including the genes, pathways, and specific drugs Inquire
Transcriptome de novo Assembly Inquire
Transcriptome Annotation Inquire
Transcriptome Annotation Inquire
Variant Annotation Inquire
Whole Genome de novo Assembly All current sequencing technologies support - Illumina, PacBio, Oxford Nanopore, 10x, Hi-C, Ion Torrent, and others. Igenbio scientists utilize a multitude of assembly strategies - denovo, reference based, hybrid, metagenomic, and others. Inquire
Base Calling Inquire
Microbiome Analysis - Quality analytics of sequence reads - State of the art sample processing using academically-proven tools such as DADA2 or Kraken2 that work on all sequencing platforms such as Illumina & Pacific Biosciences. - Fast and accurate taxa identification using state-of-the-art machine learning algorithms that can identify taxa down to the species level. - Supports public databases (such as Silva, Gree… Inquire

Genotypic Technology

NGS provider India

Genotypic Technology is the first genomics company based in India with a state-of-the-art, ISO 9001:2008 accredited, SAP-enabled, 12,000 square feet facility in Bangalore. Our high-throughput facility enables us to offer customized services for experiment design consultation, protocol optimization, microarray and probe designing, next-generation sequencing (NGS), and bioinformatics solutions to clients from academia, biotech, and pharma sectors worldwide.

We have been providing high-quality sequencing services, including whole-genome sequencing (WGS), transcriptome sequencing, shotgun metagenome sequencing, and de-novo assembly since 2000. Our skilled team has experience in working with genomes of all sizes and nucleic acids from various sources on Illumina, Oxford Nanopore, and other platforms. We have developed targeted panels for various viruses like Adenovirus, KFDV, SARS-CoV-2, Dengue, and pipelines for predicting virulent strains that may be difficult to treat with conventional antibiotics.

Our broad range of metagenome services includes targeted and whole-genome metagenome and metatranscriptome sequencing. Our long amplicon metagenome approach provides the best resolution of microbes up to the sub-species level, while whole-genome metagenome sequencing enables the identification of gene clusters, resistome, and novel pathways in a given environment. We also specialize in Ribo-footprinting and RNA immunoprecipitation sequencing, ChIP sequencing, and targeted methylation sequencing.

Years in service: 25

Other services offered by Genotypic Technology:

Service Description Price
Differential Gene Expression Analysis Differential Gene expressions, SNP variants and annotations with known reference, SSR discovery $69.00 USD (per sample)
Transcriptome Mapping $25.00 USD (per sample)
Custom scripting and special projects Bioinformatics support for 1 day - includes skype/webex consultation with detailed report. 120.00
Read Filtering and Cleaning $2.00 USD (per sample)
Exome Analysis Exome analysis - from raw data to VCF files and annotations from dbSNP, 1000 genome, COSMIC, SIFT, Polyphen2 and more $45.00 USD (per sample)
ChIP-Seq Analysis $250.00 USD (per sample)
Metagenomic Analysis $25.00 USD (per sample)
Transcriptome de novo Assembly Denovo transcriptome assembly with differential gene expression values. $600.00 USD (per sample)
Whole Genome de novo Assembly $2900.00 USD (per sample)
Base Calling $20.00 USD (per hour)

TACGenomics

United States of America

TACGenomics has a team composed of bioinformatician, molecular biologist and computer scientist who are all at Ph.D. level. Our team has the experience of hundreds of NGS data analysis projects from all over the world. The mission of TACGenomics is to help our customer to solve the biological questions. After computation analysis completed by the bioinformatician, our molecular biologist will interpret the analyzed data carefully, provide more insight into your project and help the publication of the project in the high impact journal.

Years in service: 9

Other services offered by TACGenomics:

Service Description Price
Differential Gene Expression Analysis Differentially expressed genes were identified using the edgeR program. Genes showing altered expression with p < 0.05 and more than 1.5 fold changes were considered differentially expressed. Goseq was used to perform the GO enrichment analysis and Kobas was used to performed the pathway analysis. $50.00 USD (per sample)
Transcriptome Mapping The reads were first mapped to the latest UCSC transcript set using Bowtie2 version 2.1.0 and the gene expression level was estimated using RSEM v1.2.15. TMM (trimmed mean of M-values) was used to normalize the gene expression. $50.00 USD (per sample)
Custom scripting and special projects $50.00 USD (per hour)
Exome Analysis Our team has successfully discovered a causal variant which lead to a mendelian disorder through analyzing 20 samples in three-generation family. The error rate of genotype we called in this family is only 0.2% which indicate that our pipeline detect all the SNV very accurately. $80.00 USD (per sample)
ChIP-Seq Analysis $80.00 USD (per sample)
Genome Mapping $50.00 USD (per sample)
Metagenomic Analysis $100.00 USD (per sample)
Methylation Analysis $100.00 USD (per sample)
Transcriptome de novo Assembly $100.00 USD (per sample)
Whole Genome de novo Assembly $1000.00 USD (per sample)
Microbiome Analysis $50.00 USD (per sample)

Diagenode

NGS provider

The Service at Diagenode are specialized in Epigenomics so we focused on Chromatin, DNa methylation and RNA studies. For chromatin we perform ChIP-seq (-qPCR) and ATAC-seq. In terms of DNA methylation we offer WGBS, RRBS, MeDIP-seq, Targeted DNA methylation, Illumina 850K EPIC Array and Mouse Methylation Array. Concerning RNA-seq we perform Total RNA-seq (rRNA depeltion), mRNA-seq (Poly-A selection), 3'RNA-seq, sncRNA-seq and miRNA-seq. We have a wide range experien,ce in terms of species and samples type, with special focus in biofluids (plasma/serum/urine cfDNA, circulating RNA, etc)

Years in service: 9

Other services offered by Diagenode:

Service Description Price
Differential Gene Expression Analysis Inquire
Other Services Inquire
ChIP-Seq Analysis Inquire
Methylation Analysis Inquire

intelliseq

Poland

I approach analytic challenges creatively with the result being novel, statistically significant and reproducible. I have high expertise on differential expression using RNA-seq.

Expertise:

I've been working with whole genome experiments for the last 10 years. I analysed more than 1000 gene expression microarrays (Illumina and Affymetrix, Human, Mouse, Rat and Pig). I analysed RNA-seq samples (total RNA and polyA RNA) from SOLiD 5500xl and Ion Proton, ChIP-seq samples from Illumina HiSEQ and DNA-seq (Exome) samples from Illumina HiSEQ. I developed several tools for functional analysis (see cremag.org) of gene lists.

Infrastructure:

I have almost unlimited access to Amazon EC2 and large server on site (two 8x core Xeon with 216 GB RAM 64GB of SAS disks)

Other services offered by intelliseq:

Service Description Price
Differential Gene Expression Analysis Inquire
Transcriptome Mapping Inquire
Custom scripting and special projects Inquire
Other Services Inquire
Read Filtering and Cleaning Inquire
ChIP-Seq Analysis Inquire
Small RNA Mapping Inquire
SNP / Indel Mapping Inquire
Metagenomic Analysis Inquire
SNP / Indel Calling Inquire
Genome Annotation Inquire
Methylation Analysis Inquire
Transcriptome Annotation Inquire
Variant Annotation Inquire

Genevia Technologies

Finland

Genevia Technologies provides a wide range of microarray and next generation sequencing data analyses, and bioinformatics services to life science companies and academia. In addition, we offer bioinformatics consulting projects at a fixed price, and genome-wide experiments done in collaboration with the top service providers.

Expertise:

Our expertise is in handling multiple microarray (expression, copy number, ChIP, methylation, etc) and next-gen sequencing (DNA-seq, RNA-seq, MeDIP-seq, ChIP-seq, GRO-seq, etc) data simultaneously and effectively, and combining them with other data such as clinical variables or pathway information. We have experience in most common mammalian systems, but especially in multiple human cancers. We have also worked on data from multiple species of lower eucaryotes and bacteria.

Infrastructure:

We have access to dedicated file storage servers, a computing cluster, a computing grid (of over 1000 CPUs), and cloud computing capabilities.

Visit our homepage to read more about us and our bioinformatics as a service: www.genevia.fi

Other services offered by Genevia Technologies:

Service Description Price
Differential Gene Expression Analysis Inquire
Transcriptome Mapping Inquire
Comparative Genome Analysis Inquire
Custom scripting and special projects Inquire
Other Services Inquire
Read Filtering and Cleaning Inquire
ChIP-Seq Analysis Inquire
Small RNA Mapping Inquire
SNP / Indel Mapping Inquire
Metagenomic Analysis Inquire
SNP / Indel Calling Inquire
SNP/SV/CNV Discovery Inquire
Targeted Capture Analysis Inquire
Small RNA Annotation Inquire
Methylation Analysis Inquire
Transcriptome de novo Assembly Inquire
Transcriptome Annotation Inquire
Variant Annotation Inquire
Base Calling Inquire

TAmiRNA GmbH

NGS provider

TAmiRNA is fully dedicated to NGS-based analysis of small RNAs and offers a fully integrated service from RNA extraction to data analysis. The small RNA-seq workflow was selected following the systematic comparison of 5 different library preparation methods, selecting the method with the highest sensitivity, reproducibility, and cost-effectiveness (https://doi.org/10.3390/ijms23031226). The small RNA-seq assay underwent analytical validation according to FDA guidelines for bioanalytical method validation. Results are published in Khamina et al., 2022. The workflow has been tested on a large variety of sample types including cells, tissues, serum, plasma, urine, synovial fluid, cerebrospinal fluid, and cell conditioned media. Low RNA input samples such as extracellular vesicles/exosome have been successfully analyzed.

The workflow is unique as it uses an in-house developed and patented a spike-in oligonucleotide mix (miND®) for quality control, batch-to-batch normalization, and absolute quantification independent of variation in small RNA composition between samples. miND® spike-ins are added to each sample during library preparation.

We have developed a tailored bioinformatic pipeline for small RNA-seq data (microRNAs, tRNA fragments, other small RNAs), which has been published as a preprint by Diendorfer et al. 2022 (https://doi.org/10.12688/f1000research.94159.1). The pipeline produces an interactive report with publication-ready figures including quality control results, miND spike-in results, mapping data, unsupervised (heatmap, PCR) and supervised (differential expression analysis) analyses. Customized analyses and multi-omic (RNA-seq/microRNA-seq) analyses can be performed on request.

Pre-sales consultation and follow-up data support is included in the service. The NGS service is implemented in our ISO13485 accredited quality management system.

Years in service: 11

Other services offered by TAmiRNA GmbH:

Service Description Price
Differential Gene Expression Analysis Input: demultiplexed FASTQ files (miRNA or mRNA dataset) Data analysis: • Trimming and Alignment to reference genome. • Gene quantification (miRNAs or mRNAs). • Exploratory data analysis: unsupervised clustering by PCA and hierarchical clustering. • Differential expression analysis (EdgeR/DeSeq2). • Reporting and interpretation support. Deliverables: • Full data report and raw data. • Results di… $50.00 USD (per sample)
Differential Gene Expression Analysis Input: demultiplexed FASTQ files (miRNA or mRNA dataset) Data analysis: • Trimming and Alignment to reference genome. • Gene quantification (miRNAs or mRNAs). • Exploratory data analysis: unsupervised clustering by PCA and hierarchical clustering. • Differential expression analysis (EdgeR/DeSeq2). • Reporting and interpretation support. Deliverables: • Full data report and raw data. • Results di… $150.00 USD (per sample)
Differential Gene Expression Analysis Input: demultiplexed FASTQ files (miRNA or mRNA dataset) Data analysis: • Trimming and Alignment to reference genome. • Gene quantification (miRNAs or mRNAs). • Exploratory data analysis: unsupervised clustering by PCA and hierarchical clustering. • Differential expression analysis (EdgeR/DeSeq2). • Reporting and interpretation support. Deliverables: • Full data report and raw data. • Results di… $60.00 USD (per sample)
Differential Gene Expression Analysis Input: demultiplexed FASTQ files (miRNA or mRNA dataset) Data analysis: • Trimming and Alignment to reference genome. • Gene quantification (miRNAs or mRNAs). • Exploratory data analysis: unsupervised clustering by PCA and hierarchical clustering. • Differential expression analysis (EdgeR/DeSeq2). • Reporting and interpretation support. Deliverables: • Full data report and raw data. • Results di… $40.00 USD (per sample)
Differential Gene Expression Analysis Input: demultiplexed FASTQ files (miRNA or mRNA dataset) Data analysis: • Trimming and Alignment to reference genome. • Gene quantification (miRNAs or mRNAs). • Exploratory data analysis: unsupervised clustering by PCA and hierarchical clustering. • Differential expression analysis (EdgeR/DeSeq2). • Reporting and interpretation support. Deliverables: • Full data report and raw data. • Results di… $70.00 USD (per sample)
Differential Gene Expression Analysis Input: demultiplexed FASTQ files (miRNA or mRNA dataset) Data analysis: • Trimming and Alignment to reference genome. • Gene quantification (miRNAs or mRNAs). • Exploratory data analysis: unsupervised clustering by PCA and hierarchical clustering. • Differential expression analysis (EdgeR/DeSeq2). • Reporting and interpretation support. Deliverables: • Full data report and raw data. • Results di… $100.00 USD (per sample)
Differential Gene Expression Analysis Input: demultiplexed FASTQ files (miRNA or mRNA dataset) Data analysis: • Trimming and Alignment to reference genome. • Gene quantification (miRNAs or mRNAs). • Exploratory data analysis: unsupervised clustering by PCA and hierarchical clustering. • Differential expression analysis (EdgeR/DeSeq2). • Reporting and interpretation support. Deliverables: • Full data report and raw data. • Results di… $80.00 USD (per sample)
Differential Gene Expression Analysis Input: demultiplexed FASTQ files (miRNA or mRNA dataset) Data analysis: • Trimming and Alignment to reference genome. • Gene quantification (miRNAs or mRNAs). • Exploratory data analysis: unsupervised clustering by PCA and hierarchical clustering. • Differential expression analysis (EdgeR/DeSeq2). • Reporting and interpretation support. Deliverables: • Full data report and raw data. • Results di… $30.00 USD (per sample)

Biosof LLC

United States of America

Expertise:

Expertise in mainly with plant genomes (wheat, tomato, potato, tobacco, rice, maize, diatoms and arabidopsis).

Infrastructure:

Access to over 800 cores (2.3Ghz and faster) SMP compute cluster. Access to over 50TB of raw storage. Computing infrastructure includes all commonly used bioinformatics software and databases. All computing infrastructure is maintained by a 24/7 IT service.

Other services offered by Biosof LLC:

Service Description Price
Differential Gene Expression Analysis Inquire
Comparative Genome Analysis Inquire
Custom scripting and special projects Inquire
Read Filtering and Cleaning Inquire
SNP / Indel Mapping Inquire
Genome Mapping Inquire
SNP / Indel Calling Inquire
SNP/SV/CNV Discovery Inquire
Genome Annotation Inquire
Transcriptome de novo Assembly Inquire
Transcriptome Annotation Inquire
Variant Annotation Inquire
Whole Genome de novo Assembly Inquire

Gringene Bioinformatics

New Zealand

Gringene Bioinformatics provides workflow optimisation services for research that involves the use of computers, enabling researchers to carry out their research faster, cheaper, and better. It is frequently the case that a repetitive task using computers can be sped up 5-10 times by the application of computing methods that are more appropriate to the task at hand.

Gringene Bioinformatics has particular skills in the following areas:

  • Theoretical Genetics
  • Next-Generation Sequencing
  • Computational scripting
  • Large-scale data analysis
  • Program language translation (porting)
  • Debugging / bug reporting

Expertise:

  • Homo sapiens (genome mapping, methylation analysis, SNP analysis, STR analysis, population clustering, haplotype analysis, differential expression analysis)
  • Environmental samples (16s rRNA mapping, large-scale BLAST analysis, taxonomy analysis)
  • Schmidtea mediterranea (transcriptome assembly, genome mapping, transcriptome mapping, differential expression analysis)
  • Saccharomyces cerevisiae (codon analysis, gradient peak analysis, genome mapping, transcriptome mapping)
  • Drosophila melanogaster (quantitative phenotyping, differential expression analysis)
  • Neisseria meningitidis (genome mapping, differential expression analysis)

Infrastructure:

Main processing workstation: 12-thread Intel "desktop" with 64GB memory and 3TB hard drive space (expandable as necessary). I encourage clients to purchase their own bioinformatics servers / workstations, and will use remote systems for analysis when available.

Other services offered by Gringene Bioinformatics:

Service Description Price
Differential Gene Expression Analysis Inquire
Transcriptome Mapping Inquire
Custom scripting and special projects Inquire
Other Services Inquire
Genome Mapping Inquire
Transcriptome de novo Assembly Inquire
Whole Genome de novo Assembly Inquire

Next Generation Intelligence

NGS provider Italy

NGI is a platform for Next Generation Sequencing data analysis. We offer a wide range of bioinformatics tools and an experienced and professional collaboration service for any type of biological data analysis. We provide both standard and customized analysis, custom softwares and pipelines development and post-sequencing support. We'll enhance and make easier your discovery process.

Expertise:

Our expertise is in the epigenetics field in mouse and human organisms.

Infrastructure:

we will provide FTP access to our storage server to upload raw data and download analyzed data.

Other services offered by Next Generation Intelligence:

Service Description Price
Differential Gene Expression Analysis Inquire
Transcriptome Mapping Inquire
Custom scripting and special projects Inquire
Other Services Inquire
Read Filtering and Cleaning Inquire
Exome Analysis Inquire
ChIP-Seq Analysis Inquire
Small RNA Mapping Inquire
SNP / Indel Mapping Inquire
Genome Mapping Inquire
SNP / Indel Calling Inquire
SNP/SV/CNV Discovery Inquire
Targeted Capture Analysis Inquire
Genome Annotation Inquire
Small RNA Annotation Inquire
Methylation Analysis Inquire
Transcriptome de novo Assembly Inquire
Transcriptome Annotation Inquire
Variant Annotation Inquire
Base Calling Inquire

ecSeq Bioinformatics

Germany

Bioinformatics solutions

ecSeq provides a variety of bioinformatics service packages suited for most everyday high-throughput sequencing experiments. We are particularly engaged in RNA-seq projects (trancriptomics, differential expression), ncRNA analysis (small RNA-seq, ncRNA annotation) and epigenome sequencing (bilsufilte and methylation analyses). Further bioinformatics solutions include SNP calling, variant annotation & prioritisation as well as development of customized algorithms.

Public workshops and eTrainings

We develop eTrainings and provide workshops for employee training in bioinformatics. Several times a year, we organize well-attended workshops on selected topics in next-generation sequencing data analysis. Test datasets are used for getting started in applying and developing bioinformatic tools.

Topics covered by our workshops include:

  • RNA-seq bioinformatics
  • Sequencing technolgies
  • Small RNA-seq data analysis
  • Genomic data visualization
  • Perl for bioinformatics
  • Programming in R

Expertise:

We have long experience in the development and application of bioinformatics methods to high-throughput sequencing experiments. These methods have been successfully applied in various experimental designs ranging from ncRNA and mRNA sequencing to genome/epigeome analyses. We have worked with sequencing data from humans, lifestock species (chicken, cow, turkey), plants and bacteria. Our employees are continuously involved in projects from national and international consortia, like the International Cancer Genome Consortium (ICGC) or the Leipzig Research Centre for Civilization Diseases (LIFE).

Infrastructure:

We have access to moderate computation resources allowing us to process ~120GB sequence data per week.

Other services offered by ecSeq Bioinformatics:

Service Description Price
Differential Gene Expression Analysis Inquire
Transcriptome Mapping Inquire
Custom scripting and special projects Inquire
Read Filtering and Cleaning Inquire
Exome Analysis Inquire
ChIP-Seq Analysis Inquire
Small RNA Mapping Inquire
SNP / Indel Mapping Inquire
Genome Mapping Inquire
SNP / Indel Calling Inquire
SNP/SV/CNV Discovery Inquire
Small RNA Annotation Inquire
Methylation Analysis Inquire
Transcriptome Annotation Inquire
Variant Annotation Inquire

ContigExpress, LLC

United States of America

ContigExpress is the leading integrated genomics data service provider. We offer genomic project management, data analysis, and bio-IT consulting services. Our unique value to our clients lies in our deep understanding of both biology and informatics. From project consultation, bio-IT infrastructure implementation, to data analysis, our experienced scientists deliver not only cost-effective customized informatic solutions but also their expert insights.

Our team consists of Ph.D.-level computational biologists with extensive training and professional practice in bioinformatics and genomic research. We understand both your cutting-edge research and your informatics challenges. We enable you and your team to extract actionable information from the vast amount of genomic data in a cost-effective and timely fashion.

We at ContigExpress strive to deliver affordable expert genomic data solutions to researchers and clinicians. We place the utmost emphasis on information confidentiality, data security, and data integrity. Please schedule a complimentary project discussion with one of our expert bioinformaticians to discover how we can help you move your genomics research forward!

Years in service: 14

Other services offered by ContigExpress, LLC:

Service Description Price
Differential Gene Expression Analysis Following is a list of common analysis items for RNA-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Gene and transcript-based quantitation, RPKM/FPKM-based quantitation, Raw hit count-based … Inquire
Other Services We are a professional bioinformatics service provider and we are happy to provide customized informatic solutions to your unique research and business needs. Please feel free to reach out to us to discuss how we can help you. Inquire
Exome Analysis Following is a list of common analysis items for Targeted Resequencing and Exome Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Local realignment 5) SNP and small indel calling 6) SNP… Inquire
ChIP-Seq Analysis Following is a list of common analysis items for ChIP-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Peaking calling with or without control samples 5) Gene assignment and peak annotation 6)… Inquire
Small RNA Mapping Following is a list of common analysis items for small RNA-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC, adaptor removal, and size selection 3) Read characterization by mapping to a reference genome sequence, known RNA families (e.g., Rfam), and known micr… Inquire
Genome Mapping Following is a list of common analysis items for Whole Genome Resequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Local realignment 5) SNP and small indel calling 6) SNP/small indel char… Inquire
Metagenomic Analysis Following is a list of common analysis items for Metagenomics Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Sequence assembly 4) Biodiversity analysis and binning 5) Gene predication and functional annotation 6) Gene Ontology and path… Inquire
SNP/SV/CNV Discovery Following is a list of common analysis items for Whole Genome Resequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Local realignment 5) SNP and small indel calling 6) SNP/small indel char… Inquire
Targeted Capture Analysis Following is a list of common analysis items for Targeted Resequencing and Exome Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Local realignment 5) SNP and small indel calling 6) SNP… Inquire
Genome Annotation Following is a list of common analysis items for Genome Annotation. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Gene prediction with or without RNASeq data 3) BLAST-based gene function annotation 4) Written project report with analysis methods, publication-ready graph… Inquire
Small RNA Annotation Following is a list of common analysis items for small RNA-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC, adaptor removal, and size selection 3) Read characterization by mapping to a reference genome sequence, known RNA families (e.g., Rfam), and known micr… Inquire
Methylation Analysis Following is a list of common analysis items for Methylation Sequencing, including MeDIP-Seq, hMeDIP-Seq, RRBS / Targeted Bisulfite-Seq, WGBS, and 5-mc RNA-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Methylation state-sensitive mapping 4) … Inquire
Transcriptome de novo Assembly Following is a list of common analysis items for De Novo Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Transcriptome assembly, scaffolding and gap closure 4) Gene annotation (molecular function, Gene Ontology and pathways) 5) SNP disc… Inquire
Transcriptome Annotation Following is a list of common analysis items for De Novo Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Project consultation 2) Transcriptome annotation (molecular functions, Gene Ontology and pathway) 3) Written project report with analysis methods, publication-ready graphics, and references Inquire
Whole Genome de novo Assembly Following is a list of common analysis items for De Novo Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Contig assembly 4) Scaffolding and gap closure 5) Gene/ORF prediction 6) Gene annotation and classification via database search and… Inquire

Station X

United States of America

We offer a powerful genomics software platform that makes various bioinformatics tasks fairly straightforward to perform and deliver to customers. We also wrap this product with various service offerings for folks interested in one-off projects that deliver results rather than just subscribing to a software solution and then do the work themselves. We are comfortable with both scenarios. We are well versed in working with RNA-Seq, Genomes, Exomes, targeted panels, miRNA-Seq, Copy Number, Gene Expression, Protein Expression, and DNA Methylation from the level of raw sequencing reads or chip data all the way through to statistically-driven and knowledge-driven interpretations.

Expertise:

We are experienced in developing bioinformatics pipelines, providing data management solutions, analyzing the data using statistical methods and knowledge driven methods, and delivering professional-grade results. We are most familiar with human genomics projects, but have experience with other organisms as well. We are most focused on supporting sequencing projects, but are very capable of supporting array and PCR-based projects as well.

Infrastructure:

We leverage Amazon Web Services for most of our storage (EBS & S3) and computational resources (EC2). We are not frivolous about security, and we can provide you with security documentation to demonstrate how we leverage cloud resources while keeping best-in-class security. We also have powerful 16-core machines in our own private cloud that we leverage for service projects as well.

Years in service: 13

Other services offered by Station X:

Service Description Price
Differential Gene Expression Analysis $1655.00 USD (flat price)
Transcriptome Mapping $100.00 USD (per sample)
Comparative Genome Analysis $2500.00 USD (flat price)
Custom scripting and special projects $275.00 USD (per hour)
Other Services Visualizations, Report Generation, Customizations to our platform, Training, Scientific support, Presentation support, etc. $300.00 USD (per hour)
Read Filtering and Cleaning $115.00 USD (per sample)
Exome Analysis $2500.00 USD (flat price)
Small RNA Mapping $100.00 USD (per sample)
SNP / Indel Mapping $100.00 USD (per sample)
SNP / Indel Calling $100.00 USD (per sample)
SNP/SV/CNV Discovery $100.00 USD (per sample)
Genome Annotation $85.00 USD (per sample)
Small RNA Annotation $85.00 USD (per sample)
Transcriptome Annotation $85.00 USD (per sample)
Variant Annotation $85.00 USD (per sample)

The Africa Genomics Centre and Consultancy (TAGCC) ltd

Kenya

TAGCC is an African company offering services in next generation sequence data analysis and consultancy in genomics. We have implemented a wide range of pipelines to analyse NGS data from various platforms including Illumina and 454. We support design and implementation of genomics and NGS based projects.

Years in service: 10

Other services offered by The Africa Genomics Centre and Consultancy (TAGCC) ltd:

Service Description Price
Differential Gene Expression Analysis We Identify differentially expressed and significant genes from RNA-seq data. Our workflow includes QC clean up, removal of ribosomal RNA contamination followed by denovo or reference based mapping. RPKM/FPKM-based quantitation. $80.00 USD (per sample)
Transcriptome Mapping Map mRNAs to either the reference or the assembled genome. $110.00 USD (per sample)
Other Services Admixture modelling and SNP phylogenetics. Use genetic data to infer the structure and evolutionary history of populations (Time is dependent on VCF/PED file size) $225.00 USD (per hour)
Read Filtering and Cleaning QC analysis, trimming and low quality reads removal. Both Raw and QC trimmed Fastq files will be made available. $24.00 USD (per sample)
Exome Analysis We analyse full exomes from raw sequence data through the process of cleaning, alignment, variant calling to analysis ready vcf file with variants effects summary. $125.00 USD (per sample)
SNP / Indel Mapping Map SNPs and Indels. $110.00 USD (per sample)
Genome Mapping Alignment of NGS data to reference genome and generate mapping statistics $60.00 USD (per sample)
Metagenomic Analysis Generating publication ready Phylogenetic trees, Alpha and beta-diversity, rarefactions, rank abundance plots, relative abundance bar plots, with integration of meta-data, etc. Inquire
SNP / Indel Calling Identify and qualify SNPs and Indels. $110.00 USD (per sample)
Base Calling Demultiplex data and convert BCL or SFF files to FASTQ files. (Time is dependent on file size) $120.00 USD (per hour)

Strand Life Sciences

India

Strand Life Sciences is a technology innovation company that has pioneered the practice of scientific intelligence in health sciences. Strand was established in 2000, with a founding theme “Algorithms for Life”. The company is an academic-spin of in India, founded by four Computer Scientists - Dr. Vijay Chandru, Dr. Ramesh Hariharan, Dr.V. Vinay, and Dr. Swamy Manohar. Since then, we have established a strong portfolio of products for biological systems research and for diagnosis and treatment of diseases. Over 2000 scientific laboratories and 100 hospitals across the world are our clients. Now, we have entered a new era guiding medical decisions using molecular insights with a new theme ‘New Generation Healthcare’.

Strand NGS-Formerly Avadis® NGS is Strand’s flagship product for analysis, management and visualization of next-generation sequencing data. It supports extensive workflows for alignment, RNA-Seq, small RNA-Seq, DNA-Seq, ChIP-Seq, MeDIP-Seq and Methyl-Seq experiments. We provide bioinformatics services using Strand NGS and price is dependent on man hours, number of samples and other factors. Please consult us for more details sales@strandngs.com

Years in service: 13

Other services offered by Strand Life Sciences:

Service Description Price
Differential Gene Expression Analysis $500.00 USD (per sample)
Exome Analysis $500.00 USD (per sample)
ChIP-Seq Analysis Inquire $500.00 USD (per sample)
SNP / Indel Mapping $500.00 USD (per sample)
SNP / Indel Calling $500.00 USD (per sample)
SNP/SV/CNV Discovery $500.00 USD (per sample)
Methylation Analysis $500.00 USD (per sample)

STAB VIDA

NGS provider Portugal

Years in service: 11

Other services offered by STAB VIDA:

Service Description Price
Differential Gene Expression Analysis Deliverables include the raw data fastq seq files, transcriptome mapping, gene expression analysis and a report (including Q score, number of reads, coverage, etc) $200.00 USD (per sample)
SNP / Indel Mapping Deliverables include the raw data fastq seq files, consensus sequence, list of genetic variants and a report (including Q score, number of reads, coverage, etc) $200.00 USD (per sample)
Genome Mapping Deliverables include the raw data fastq seq files, consensus sequence and a report (including Q score, number of reads, coverage, etc) $200.00 USD (per sample)
Whole Genome de novo Assembly Deliverables include the raw data fastq seq files, list of contigs and a report with results (including Q score, number of reads, coverage etc) $200.00 USD (per sample)
Base Calling Deliverables include the raw data fastq seq files Inquire

Computomics

Germany

Bioinformatics Services for Plant Scientists and Breeders by Computomics

At Computomics.com, we deliver in-depth NGS analyses. We start by identifying your breeding or research goals, devise a sequencing strategy to achieve them and define the project deliverables and timeline through an initial consultation. Our methods include the latest algorithms from the bioinformatics community.

We protect the security of your data. We use high-performance servers in a high-security data center with two-factor access control mechanisms. During the analysis, we use transparent, reliable processes and quickly deliver highly reproducible results in constant feedback with you, via virtual or onsite meetings at your location.

Our NGS products are exclusively focusing on plant species and their interacting microbes, and include: 

  • Reference genome assembly: experience with polyploids and genomes up to 22 Gbp
  • Genome annotation: ab initio gene and transcript isoform prediction, protein function, ncRNA annotation
  • Genomic variance analysis and comparison: for marker development, phylogenetic studies, and comparative genomics
  • Bulk segregation analysis, genotyping, marker development
  • Differential gene expression, de novo transcriptome assembly
  • World’s fastest, most accurate metagenomics
  • Statistically sound epigenetics
  • Genomic selection with continuous model improvement

Computomics collaborates with world-leading scientists, opening up an unprecedented opportunity for breeders and plant scientists. We provide data of the highest possible quality that expedite your crop improvement programs.

Years in service: 11

Other services offered by Computomics:

Service Description Price
Differential Gene Expression Analysis Gene expression studies, or RNAseq allow you to sequence the entire transcriptome of a plant, and provide valuable applications in crop improvement programs We and our collaborators have published peer reviewed methods for accurate gene expression analysis. Our RNAseq analyses can determine exact gene expression levels including splice variants. Using machine learning techniques, we identify dif… Inquire
Comparative Genome Analysis We excel at managing complex crop genomic variance studies. Our analysis can help you obtain a set of genomic markers to enhance rational and controlled breeding procedures. Markers may include single nucleotide polymorphisms (SNPs), insertions and deletions (InDels), copy number variations (CNVs) or structural variants (SVs). Taking into account the properties of your plant of interest and the … Inquire
Other Services Bioinformatics Consulting In addition to our next-generation sequencing (NGS) products and services, We also offer individual consulting services. With a team of scientists and partners who are thought leaders in crop genomics, we give impartial advice, independent of any sequencing platform, technology or tool suite. Each consultation is unique, please contact us to receive a quote for your sp… Inquire
Other Services Introgression and Insertion Delineation Next-generation sequencing is a great tool for molecular characterisation of seeds with genetic modifications or introgressions. We can provide answers to many regulatory and safety related questions, such as: At how many sites was the DNA integrated into the plant genome? What is the exact sequence of each insert? Is the sequence rearranged with respect t… Inquire
Other Services Genomic Selection with Continuous Model Improvement Genomic Selection with Continuous Model Improvement Genomic selection is a highly successful strategy to predict breeding values in plants. Advances in sequencing and high-throughput variant discovery enable the collection of tens of thousands of markers for hundreds of plants, providing exciting opportunities for unleashing the full power of g… Inquire
Read Filtering and Cleaning Inquire
Metagenomic Analysis World’s Fastest, Most Accurate Metagenomics Plants interacts constantly with soil-borne microbes. These interactions vary from symbiotic to pathogenic. In a metagenomics study of the rhizosphere, DNA or RNA are sequenced using next generation sequencing instruments. Sequences that do not originate from the plant host are analysed to identify genes and species contained within the sample. A tax… Inquire
Genome Annotation We perform de novo genome annotation using the latest in silico predictive approaches and RNAseq reads. We offer two machine learning-based gene prediction methods that can be trained to recognise biological features in your crop’s genome. The resources we use to build an annotation map include existing annotations for related organisms, RNAseq data, and PacBio complete isoforms. We use all avai… Inquire
Methylation Analysis Statistically Sound Epigenetics Non-genetic factors affect crops traits and phenotypes. Identifying epigenetic patterns allow breeders and plant scientists to uncover expression correlations and non-genetically inherited gene regulation patterns. We specialize in crop epigenetics. Methylation of cytosine residues is a known mechanism for gene silencing and gene expression regulation. We use bi… Inquire
Whole Genome de novo Assembly We have a deep understanding of both de novo and reference-based genome assembly of large crop genomes. It is crucial to first develop an effective strategy before selecting the appropriate sequencing technology and bioinformatics tools. A de novo genome assembly project must address sources of error up front, like sequence bias and read quality. A crucial point is quality control. We compare o… Inquire

Girihlet Inc.

NGS provider United States of America

We specialize in esoteric parts of the genome offering services (sample prep, sequencing and analyses) in areas such as 1) mitochondrial DNA sequencing, 2) TCR repertoire sequencing and 3) small RNA sequencing.

We also perform routine services such as 4) mRNA-seq and 5) whole-exome sequencing. We have prepared samples from mouse, human, drosophila, as well as organisms such as zebrafish and Bats. We have developed novel, custom analytical pipelines for data analysis from each species.

Years in service: 9

Other services offered by Girihlet Inc.:

Service Description Price
Differential Gene Expression Analysis 1. Gene-level expression estimation (NCBI RefSeq gene set) with annotation for each sample. 2. Transcript-level expression estimation (NCBI RefSeq transcript set) with annotation for each sample. 3. Gene-level differential expression assessment with annotation for one pairwise comparison. 4. Transcript-level differential expression assessment with annotation for one pairwise comparison. 5. En… $225.00 USD (per sample)
Small RNA Mapping mapping and differential expression assessment with annotation for one pairwise comparison. $225.00 USD (per sample)
SNP / Indel Calling novel custom made pipelines (published) to call SNPs and INDEL effectively. $225.00 USD (per sample)
Whole Genome de novo Assembly $350.00 USD (per sample)

MedGenome, Inc.

NGS provider United States of America

MedGenome has a next generation sequencing lab based in South San Francisco housing Illumina's NovaSeq, HiSeq X, HiSeq 2500 & MiSeq machines. We specialize in end to end Genomic Services including: DNA/RNA extraction, library prep, sequencing, standard analysis, and advanced analysis.

We offer whole genome, whole exome, RNA sequencing (including low input options), TCR seq (alpha/beta, gamma/delta, FFPE), BCR and single cell sequencing services. We also help labs sequence their pre-made libraries. We offer proprietary tumor microenvironment analysis and neo-epitope prediction as part of our advanced bioinformatics services.

Years in service: 11

Other services offered by MedGenome, Inc.:

Service Description Price
Differential Gene Expression Analysis We offer RNA analysis services. You can provide us FASTQ files we will will provide gene expression, differential expression, pathway analysis reporting $100.00 USD (per sample)
Exome Analysis Alignment and variant calling (BAM and VCF files) Optional somatic mutation analysis and annotation $100.00 USD (per sample)

NXT-Dx

NGS provider Belgium

At NXT-Dx we can offer SE50, PE50 and PE100 sequencing on the Illumina HiSeq. On top of this we can also offer different sequencing settings on the Illumina MiSeq and shortly we will also be able to offer sequencing on the Illumina NextSeq.

We can offer sequencing of already prepared libraries but we can also offer full-scope projects whereby we receive cells, tissue, gDNA or RNA and take care of the sample preparation, library prep, sequencing and bio-informatics analysis.

We have worked with samples from all kind of species (mammalian, plant, bacterial) and all kind of cell types.

We pride ourselves in having close contact with our customers and only one single contact point. Also after the delivery of the data, we remain available to answer any questions customers might have on their data, their analysis, etc.

Years in service: 13

Other services offered by NXT-Dx:

Service Description Price
Differential Gene Expression Analysis $170.00 USD (per hour)
Transcriptome Mapping $170.00 USD (per hour)
Comparative Genome Analysis $170.00 USD (per hour)
Custom scripting and special projects $170.00 USD (per hour)
Read Filtering and Cleaning $170.00 USD (per hour)
Exome Analysis $170.00 USD (per hour)
ChIP-Seq Analysis $170.00 USD (per hour)
Small RNA Mapping $170.00 USD (per hour)
Genome Mapping $170.00 USD (per hour)
Targeted Capture Analysis $170.00 USD (per hour)
Genome Annotation $170.00 USD (per hour)
Small RNA Annotation $170.00 USD (per hour)
Methylation Analysis $170.00 USD (per hour)
Transcriptome Annotation $170.00 USD (per hour)
Variant Annotation $170.00 USD (per hour)
Base Calling $170.00 USD (per hour)

Beckman Coulter Genomics

NGS provider United States of America

Beckman Coulter Genomics offers next generation sequencing services designed to meet the evolving sequencing needs of academic, biotechnology and pharmaceutical researchers worldwide. A comprehensive range of next generation sequencing services is available utilizing platforms from Illumina and Roche.

End to end solutions are offered allowing tailoring of projects to your specific needs. A wide variety of bioinformatics packages are available and results consultation is provided to ensure you understand the data returned to you. For the quickest service we accept pre-made libraries for sequencing only projects.

• Expert scientists consult on project design to ensure appropriate experimental approach • Beckman Coulter instrumentation utilized for fully automated library construction and target enrichment with enhanced reproducibility and reliability • Bioinformatics scientists oversee all data analysis to ensure quality
• Videoconference provided for report review and results discussion

Trusted Partner • Over 20 years sequencing experience • 1,500+ customer publications • 200+ successful audits • Experienced staff from well-known institutes of academic and commercial excellence • Contributed sequencing data to • >10 genome projects including mouse, cat, dog and salmon • >100 Microbial and Fungal genomes

Years in service: 18

Other services offered by Beckman Coulter Genomics:

Service Description Price
Differential Gene Expression Analysis $150.00 USD (per sample)
Read Filtering and Cleaning Inquire
Exome Analysis $250.00 USD (per sample)
Metagenomic Analysis Assembly including demultiplexing and standard run report Inquire
SNP / Indel Calling $250.00 USD (per sample)
Targeted Capture Analysis $250.00 USD (per sample)
Small RNA Annotation $150.00 USD (per sample)
Variant Annotation $250.00 USD (per sample)

SciBerg

Germany

We offer computational analyses of Next-Generation Sequencing data (Illumina and Ion Torrent platforms), including RNA-seq, small RNA-seq, DNA-seq, Bisulfite-seq and ChIP-seq. Our bioinformatics support can be fully customized for your research needs, the scope and objectives of the study. We apply only up-to-data well-proven software and pipelines working under Unix/Linux environment. Optionally, our experts can help to interpret the obtained results from the scientific point of view, provided some of them are working in a close research field.

Other services offered by SciBerg:

Service Description Price

UT Health Science Center at San Antonio Genome Sequencing Facility

NGS provider United States of America

The Genome Sequencing Facility (GSF) at Greehey Children’s Cancer Research Institute in University of Texas Health Science Center at San Antonio utilizes state-of-the-art genomic platforms to generate high-quality genomic data and provides support to its analysis. The GSF provides genomic service of Illumina next generation sequencing (both HiSeq and MiSeq platforms) for researchers both inside and outside Institute, University, other academic institutions as well as in the biotechnology and pharmaceutical industries. We welcome opportunities to partner on many kinds of research projects regardless of size, both as scientific collaborations and on a fee-for-service basis. Please contact us to discuss how we can help you in your research.

In March 2016, The GSF was awarded $600,000 NIH Shared Instrument grant (S10 grant 1S10OD021805-01) to purchase Illumina HiSeq 3000 to upgrade the sequencing platform. Illumina HiSeq 3000/4000(3000 carries one flow cell vs HiSeq 4000 with two flow cell stations) is the latest and most efficient sequencing platform in Illumina NGS market. It provides greater efficiency in terms of high-throughput, faster turn-around-time and cheaper cost.

Years in service: 13

Other services offered by UT Health Science Center at San Antonio Genome Sequencing Facility:

Service Description Price
Differential Gene Expression Analysis $100.00 USD (per sample)

HybridStat Predictive Analytics

Greece

HybridStat is a company bringing together a team of highly qualified and motivated scientists and developers, whose expertise spans a variety of statistics and computer science domains. Main HybridStat’s services are centered on bioinformatics, biostatistics and analytics of high-throughput data derived from modern biological technologies such as Next Generation Sequencing (NGS), DNA microarrays and Mass Spectrometry. In addition, HybridStat offers customized software solutions regarding the above.

Regarding NGS, HybridStat offers a variety of one-stop shop data analysis and analytics services, spanning from genome alignments and preprocessing of raw short read fragments, up to analytical and specialized reports and figures describing the results of various NGS protocols including RNA-Seq (quality control, differential expression and splicing analysis, biochemical pathway enrichments etc.), ChIP-Seq (data normalization and peak calling, gene-binding site associations, methylation profiles, motif finding etc.), Whole Exome and Whole Genome Sequencing (data preprocessing, variant calling, filtering, annotation and interpretation, etc.) and Single Cell Sequencing data analysis, using both open source and optimized proprietary pipelines.

HybridStat, can also offer complete support to your organization through its advanced Whole Exome Sequencing analytics platform Clingon (www.clingon-mds.com). Clingon is a complete, integrated one-stop clinical genomics and medical decision support platform which performs data analysis from raw data up to the generation of clinical reports. It uniquely integrates and curates a handful of resources regarding gene-disease and gene product-drug associations as well as curated variant annotation data towards more timely and accurate results and the optimal design of personalized treatment plans.

Years in service: 10

Other services offered by HybridStat Predictive Analytics:

Service Description Price
Differential Gene Expression Analysis A fully descriptive and interactive report is provided. $300.00 USD (flat price)
Comparative Genome Analysis $60.00 USD (per hour)
Custom scripting and special projects $70.00 USD (per hour)
Other Services $70.00 USD (per hour)
Read Filtering and Cleaning $25.00 USD (per sample)
Read Filtering and Cleaning $30.00 USD (per sample)
Read Filtering and Cleaning $20.00 USD (per sample)
Exome Analysis Exome analysis includes quality control, alignment to the reference genome, alignment statistics, variant calling, variant annotation with our proprietary annotation pipeline which guarantees better results especially in indels and gene-disease association reports. $150.00 USD (per sample)
Exome Analysis Exome analysis includes quality control, alignment to the reference genome, alignment statistics, variant calling, variant annotation with our proprietary annotation pipeline which guarantees better results especially in indels and gene-disease association reports. $170.00 USD (per sample)
Exome Analysis Exome analysis includes quality control, alignment to the reference genome, alignment statistics, variant calling, variant annotation with our proprietary annotation pipeline which guarantees better results especially in indels and gene-disease association reports. $200.00 USD (per sample)
ChIP-Seq Analysis ChIP-Seq analysis includes alignment to the reference genome, quality control, enriched region (peak) calling and association of enriched regions with nearby genes. $70.00 USD (per sample)
ChIP-Seq Analysis ChIP-Seq analysis includes alignment to the reference genome, quality control, enriched region (peak) calling and association of enriched regions with nearby genes. $85.00 USD (per sample)
ChIP-Seq Analysis ChIP-Seq analysis includes alignment to the reference genome, quality control, enriched region (peak) calling and association of enriched regions with nearby genes. $100.00 USD (per sample)
SNP / Indel Mapping $30.00 USD (per sample)
SNP / Indel Mapping $25.00 USD (per sample)
SNP / Indel Mapping $40.00 USD (per sample)
Genome Mapping $25.00 USD (per sample)
Genome Mapping $20.00 USD (per sample)
Genome Mapping $30.00 USD (per sample)
SNP / Indel Calling $40.00 USD (per sample)
SNP / Indel Calling $45.00 USD (per sample)
SNP / Indel Calling $50.00 USD (per sample)
Variant Annotation Variant annotation is performed with our proprietary annotation pipeline which guarantees better results especially in indels. $40.00 USD (per sample)
Variant Annotation Variant annotation is performed with our proprietary annotation pipeline which guarantees better results especially in indels. $50.00 USD (per sample)
Variant Annotation Variant annotation is performed with our proprietary annotation pipeline which guarantees better results especially in indels. $60.00 USD (per sample)
Whole Genome de novo Assembly $1000.00 USD (flat price)

ideas4biology Ltd.

Poland

DATA ANALYSIS Routine NGS data analysis in the area of genomics and transcriptomics, such as: - Gene expression and differential expression analysis - De novo and ab initio transcriptome assembly - Small RNA analysis - Genome variant calling and annotation

Customized tasks, including: - Identification of long noncoding RNAs - Identification of ta-siRNAs - Isomir and miRNA editing analysis - Annotation of non-model organisms - Building transcriptome-wide maps of RNA-RNA interactions

WORKSHOPS We offer workshops in a broad spectrum of bioinformatics applications, including: - RNA-Seq data analysis (4 days) - NGS in medical research (4 days)

EXPERIENCE We’ve been in the market since 2013 and came into collaboration with hundreds of customers. We’ve been working on model and non-model organisms, including viruses, bacteria, fungi, plants, animals, and human. We are part of research consortium aiming at development of personalized medicine services for diagnosis and treatment of lung cancers. We are also actively conducting research projects in different areas of genomics and transcriptomics, which gives us expertise in standard and up-to-date bioinformatics solutions.

INFRASTRUCTURE We have access to dedicated file storage and computational servers, with virtually unlimited (on demand) capacity.

Years in service: 11

Other services offered by ideas4biology Ltd.:

Service Description Price
Differential Gene Expression Analysis This includes: - quality filtering - adapter trimming - optionally: discarding rRNA-mapping reads or other contaminants - read mapping - expression estimation - differential expression analysis - a report, result data files and diagnostic plots Differential expression analysis itself, with expression estimations from customer: $30. $185.00 USD (per sample)
Transcriptome Mapping This includes: - quality check and filtering - adapter trimming - optional: discarding rRNA-mapping reads and other contaminants - read mapping (default or customized settings) - read mapping report and result files $100.00 USD (per sample)
Other Services Identification of long noncoding RNAs in animals and plants. This includes: - assessment of protein-coding potential with at least two independent methods - sequence length filtering - discarding of known, coding transcripts - discarding known noncoding RNAs other than lncRNAs - optionally: genomic context-driven filters - other filtering steps, depending on data availability, such as tran… $50.00 USD (per hour)
Read Filtering and Cleaning This includes: - Quality report - Quality filtering - Adapter trimming - Optionally: discarding rRNA-mapping reads or other contaminants $46.00 USD (per sample)
Small RNA Mapping This includes: - quality check and filtering - adapter trimming - read mapping to custom sequences (genome, transcriptome) - read mapping quality assessment - read mapping report This may be followed by miRNA identification or similar tasks, priced separately. $130.00 USD (per sample)
Genome Mapping This includes: - quality check and filtering - adapter trimming - optionally: discarding rRNA-mapping reads or other contaminants - read mapping with varied tools and settings - accomodated to customer's needs - quality report $85.00 USD (per sample)
SNP / Indel Calling This includes: - quality check and filtering - adapter trimming - read mapping and further processing of mapping results - SNP / Indel calling Both somatic and germline variants may be called. There is possibility to call structural variants as well, priced separately. $165.00 USD (per sample)
Small RNA Annotation This includes: - quality check and filtering - adapter trimming - read mapping to databases of noncoding RNAs, such as miRBase, DASHR or RFAM - annotation report $150.00 USD (per sample)
Methylation Analysis This includes: - quality check and filtering - adapter trimming - read mapping - calling methylated and unmethylated cytosines - differential methylation analysis: finding differentially methylated bases and regions $250.00 USD (per sample)
Transcriptome de novo Assembly This includes: - quality check and filtering - adapter trimming - optionally: discarding rRNA-mapping reads or other contaminants - transcriptome de novo assembly - a quality report and a transcriptome in FASTA format For further annotation of the transcriptome, please see our offer for "Transcriptome annotation". $250.00 USD (per sample)
Transcriptome Annotation This includes: - BLAST searches against databases of proteins and noncoding RNAs, including miRBase, RFAM, UniProt (Swiss-Prot) - hmmscan search against PFAM protein domains - assignment of GO terms to genes - assignment of KEGG pathways to genes - a report and annotation files with per gene details $125.00 USD (per sample)
Variant Annotation This includes: - prediction of possible consequences associated with predicted variants, such as affecting splicing of protein coding capacity - comparison with known variants from public databases - a report and result files $150.00 USD (per sample)

Omega Bioservices

NGS provider United States of America

Our facility is unique because we offer the full range of NGS service from sample extraction through to data analysis. Sample extraction capabilities and expertise cover the entire spectrum of both environmental and clinical sample types.

Years in service: 11

Other services offered by Omega Bioservices:

Service Description Price
Differential Gene Expression Analysis Custom bioinformatics for non-model organisms, or other unusual cases. Does not include setup fee. $110.00 USD (per sample)
Differential Gene Expression Analysis Identify differentially expressed genes among samples using RNA-seq technique. Human, mouse, rat, fruit fly, cattle, pig, chicken, zebrafish, C. elegans, maize, thale cress, Japonica rice (Oryza sativa) and yeast, up to 7.5gb/sample. $56.00 USD (per sample)
Transcriptome Mapping Map mRNAs to either the reference or the assembled genome. $332.00 USD (per sample)
Custom scripting and special projects We provide study specific bioinformatics analysis (known as tertiary analysis). such as (not limited to) 1) process secondary sequencing data analysis for a variety of platforms such as Nanostring, Nanopore, single cell expression. 2) integrative analysis across sequencing platforms (such as DNA-seq, RNA-seq, Chip-seq) 3) integrate meta/clinical information, perform association study and build p… $60.00 USD (per hour)
Read Filtering and Cleaning Examination of sequencing quality and removal of low quality reads prior to downstream analysis provided free of charge with sequencing service if desired. $110.00 USD (per sample)
Exome Analysis Whole exome sequencing involves capturing the coding region of the genome, or exons (EXpressed regiONS). SNVs and indels are the most important and abundant types of variation in exons. Human exome analysis provided free of charge with sequencing service. $332.00 USD (per sample)
ChIP-Seq Analysis ChIP-Seq is a technique to identify DNA loci bound by a specific protein. The standard output of ChIP-seq analysis includes peak call and motif enrichment at binidng sites. $332.00 USD (per sample)
Small RNA Mapping Small RNA (miRNA, lincRNA, snoRNA, snRNA, tRNA) libraries will be mapped to the reference genome and annotated using public databases e.g. miRBase. $221.00 USD (per sample)
SNP / Indel Mapping Mapped to the reference genome and annotated using public database. Analysis for human, mouse, and rat provided free of charge with sequencing service. $332.00 USD (per sample)
Genome Mapping Genome mapping is a technique used to assign the location of a particular gene on a chromosome and measure their relative locations and distances between genes. Mapping to many model organisms provided free of charge with sequencing service. $110.00 USD (per sample)
Metagenomic Analysis Metagenomic analysis involves the identification and quantification of genetic material from environmental, uncultured microorganisms. Analysis involving only 16S rRNA amplicon sequences are provided free of charge with sequencing service. $551.00 USD (per sample)
SNP / Indel Calling Identify SNPs and Indels in the region of interested, using DNA sequencing. Analysis for human, mouse, and rat provided free of charge with sequencing service. $332.00 USD (per sample)
SNP/SV/CNV Discovery Variants discovery. Analysis for human, mouse, and rat provided free of charge with sequencing service. $332.00 USD (per sample)
Targeted Capture Analysis Variant call, gene annotation. Provided free of charge with sequencing service. $332.00 USD (per sample)
Genome Annotation Annotation is the process by which pertinent information about these raw DNA sequences is added to the genome databases. This involves describing different regions of the sequence and identifying which regions can be called genes. $221.00 USD (per sample)
Small RNA Annotation Small RNA (miRNA, lincRNA, snoRNA, snRNA, tRNA) libraries will be mapped to the reference genome and annotated using public databases e.g. miRBase. $332.00 USD (per sample)
Methylation Analysis The processing of bisulfite sequencing data includes sequence alignment and the quantification of absolute DNA methylation at base resolution. Methylation analysis for data generated from the Illumina TruSeq kit are provided free of charge with sequencing service. $553.00 USD (per sample)
Transcriptome de novo Assembly Identify and quantify putative mRNA transcripts using RNA-seq data for unannotated species. $553.00 USD (per sample)
Transcriptome Annotation Annotate or predict functions of transcribed genes using well know gene ontology tools. $332.00 USD (per sample)
Variant Annotation Identified variants will be mapped to the reference genome and annotated using public database. Analysis for human sequences provided free of charge with sequencing service. $332.00 USD (per sample)
Whole Genome de novo Assembly Prices vary according to genome type. Please contact our Science Project Team. Some small genome assembly provided free of charge with sequencing service. $3315.00 USD (per sample)
Base Calling Demultiplex data and convert BCL files to FASTQ files $110.00 USD (per sample)

Applied Biological Materials Inc.

NGS provider Canada

Committed to making newer technologies attainable to modern researchers, abm offers a wide range of sequencing services on the advanced Illumina® sequencing platforms at accessible prices and rapid turnaround times. abm's premium NGS services will not only save valuable time and money, but also provide the most reliable and comprehensive solution for the project's needs.

Advantages of using our NGS services: -dedicated NGS specialists to help with experimental design and data analysis -customizable bioinformatics analysis to suit your project needs -strict quality control at multiple steps in library preparation and sequencing -RNA-seq, miRNA-seq, WGS, metagenomics, Amplicon-Seq and more!

What types of bioinformatics analysis will be done? If the reference genome is available (i.e. human or mouse), read mapping and alignment to the reference genome is included in the service. -Data is available in industry standard formats: FASTQ (default), SFF or BAM. Other formats available upon request (additional fees may apply). -RNA-seq includes: Read mapping and gene expression level estimation

Our data report files are provided in formats that can be viewed with any standard text viewers.

Years in service: 10

Other services offered by Applied Biological Materials Inc.:

Service Description Price

TB-SEQ, Inc.

NGS provider United States of America

TB-Seq Inc. is a life-science company devoted to the development and application of experimental and computational procedures for functional (meta)genomics analysis of prokaryotic and eukaryotic organisms and communities based on the ribosome profiling NGS platform technology (RIBO-seq) and on computational analysis of sequencing data. TB-Seq develops new experimental protocols and computational tools applicable to different biological system, and offers related services. Our team combines decades of experience in research and development in computational sequence analysis, molecular biology and biochemistry, in experimental analysis of nucleic acids, and in protein and nucleic acid sequence and structure computational analysis. TB-SEQ Inc. is located in Palo Alto, at the core of the San Francisco peninsula Biotech hub and in close proximity to Stanford University Campus and facilities.

TB-SEQ is the only commercial provider of RIBO-seq analysis. We offer competitive pricing, fast turn-around, highest quality of execution, and customized project design and execution to fit your needs from data collection, through data analysis, to result summary and high-quality pictures for publication purposes.

Other services offered by TB-SEQ, Inc.:

Service Description Price
Differential Gene Expression Analysis We have the computational capabilities to perform customized analyses on your sequencing data, using available software packages, our suite of bioinformatics tools, or by developing new analytical tools according to your needs. Whatever the information you are looking to extract from your data, we will be happy to discuss with you the most appropriate computational-analysis design, and to execute… $150.00 USD (per hour)

Minnesota Informatics

United States of America

Minnesota Informatics specializes in the analysis of genomic and expression data for reference and non-reference species. We are experienced in the QC, mapping/assembly, quantification and evaluation of NGS data for RNA-Seq, SNP and Single Cell sequencing projects. We have worked with human and model mammal organisms as well as plant and bacterial genomes.

We distill the large NGS datasets down to manageble tables and graphics of significant, differentially expressed or variant genes/loci.

Years in service: 13

Other services offered by Minnesota Informatics:

Service Description Price
Differential Gene Expression Analysis Identify significant genes for RNA-seq or expression data. May be included with mapping projects and price will vary with project size. Inquire
Transcriptome Mapping Inquire
Read Filtering and Cleaning QC analysis, trimming and low quality masking/removal. Inquire
ChIP-Seq Analysis Inquire
SNP / Indel Calling Identify and qualify SNPs based on transcriptome or regions of interest. Pricing negotiable by project or by the sample. Inquire
SNP/SV/CNV Discovery Inquire
Transcriptome de novo Assembly Inquire
Transcriptome Annotation Inquire
Whole Genome de novo Assembly Bid will vary with type and size of genome. Inquire

Bioinformatics Unit, Panacea Biosciences

NGS provider India

Other services offered by Bioinformatics Unit, Panacea Biosciences:

Service Description Price
Read Filtering and Cleaning $40.00 USD (per sample)
Exome Analysis End to End Exome-Seq Data Analysis $75.00 USD (per sample)
ChIP-Seq Analysis we present step-by-step guidelines for the computational analysis of ChIP-seq data. We address all the major steps in the analysis of ChIP-seq data: sequencing depth selection, quality checking, mapping, data normalization, assessment of reproducibility, peak calling, differential binding analysis, controlling the false discovery rate, peak annotation, visualization, and motif analysis. $80.00 USD (per sample)
Genome Mapping Available only for Human, Mouse and available sequenced geneomes $75.00 USD (per sample)
SNP/SV/CNV Discovery End to End variant analysis $70.00 USD (per sample)
Small RNA Annotation Available only for Human, Mouse and available sequenced geneomes $60.00 USD (per sample)
Base Calling Base calling is the process of assigning bases (nucleobases) to chromatogram peaks. One computer program for accomplishing this job is Phred base-calling, which is a widely used basecalling software program by both academic and commercial DNA sequencing laboratories because of its high base calling accuracy. $50.00 USD (per sample)

CD Genomics

NGS provider United States of America

We specialize in the services of DNA sequencing, genotyping, DNA library construction and aptamer development. Shotgun Library Sequencing, cDNA Library Sequencing, SAGE Library Sequencing, Whole Genome Sequencing and Primer Walking Sequencing. we offer high quality Re-sequencing & SNP Discovery Services. Quite a few of our staff scientists once participated in the International HapMap Project too.

extensive experience in whole genome shotgun sequencing services. Beginning from bacterial cells or genomic DNA, we provide you with accurate genome consensus sequences. We are also experienced in genome annotation and comparative genomics research. Notably our staff scientists have finished a number of whole microbial genome sequencing projects, such as the genomes of Pseudomonas bathycetes, Bacillus thuringiensis, Thermoanaerobacter tengcongensis, Streptococcus suis, and quite a few virus genomes. In addition, our in-house Laboratory Information Management System (LIMS) as well as manual basecalling ensures the highest service quality.

CD Genomics has been offering professional DNA library construction services for over 5 years. Hundreds of various cDNA libraries (such as standard cDNA library, large insert cDNA library, normalized cDNA library and subtracted cDNA library) and genomic DNA libraries (including short-insert plasmid shotgun library, large-insert plasmid shotgun library, whole genome shotgun library, Fosmid library, Cosmid library, MiniBAC and BAC library) have been constructed in our lab

CD Genomics has been dedicated to provide a full range of services to develop high quality customized aptamers for research, diagnostic and therapeutic applications. Services offered by CD Genomics include aptamer synthesis, aptamer generation, cell aptamer selection, aptamer design and modification, negative selection and so on.

Years in service: 19

Other services offered by CD Genomics:

Service Description Price
Other Services We provide statistical and bioinformatic data analysis services that help explain the large amounts of data commonly generated by next generation sequencing and genotyping experiments. Our bioinformatic staff consists of all PhD-level scientists trained in bioinformatics, biology and statistics. The software infrastructure for analysis is a combination of custom-built and open-source software. O… Inquire
SNP / Indel Mapping CD genomics can help you analyze genetic variation efficiently to meet diverse research needs. By utilizing Affymetrix and Illumina array platforms, we support high-throughput and multiplex processing to meet diverse research needs, delivering high-quality data at a low per-sample cost. Advantages of SNP Microarray Custom, flexible, and scalable; High call rates (> 99%) and high accuracy; Cost-… $80.00 USD (per sample)
Metagenomic Analysis Key Features and Advantages Longest average read lengths, with~50% of reads longer than 50kb, which exceeds the size of repetitive elements in the average bacterial genome. No DNA amplification. Highest consensus accuracy, low sequencing-context bias Novel bioinformatics analysis programs and pipelines Well-experienced personnel Sample Requirements: gDNA≥5 ug Sequencing Strategy: PacBio Platfo… 120.00

Leucine Rich Bio

India

Leveraging the expanding prospects of microbiome research, Leucine Rich Bion has integrated a robust computational pipeline "MetaRich" into a user-friendlyplatform for comprehensive analyses of any microbiome data.

After rigorous testing & validation of several leading microbiome analysis pipelines, tools & databases, we have compiled “MetaRich” to analyze both 16s rDNA & shotgun metagenomes, duly supplemented by our in-house computational tools. MetaRich will assist both researchers & industry personnel who are in pursuit of discovering biological insights within complex microbial systems & will ease the arduous task of large-scale microbiome data analysis.

Years in service: 10

Other services offered by Leucine Rich Bio:

Service Description Price
Microbiome Analysis For Individual Samples Abundance data - Raw & % Normalized Abundance Bar plots - Raw & % Normalized Pie charts - Kingdom through Phylum Alpha diversity Plots & index value table AMR Prediction Comparative Analyses Differential abundance data (across groups) Abundance Bar plots Raw & % Normalized Alpha diversity Plots & index value table Beta diversity Plots & index value table PCoA analysis & pl… $9.00 USD (per sample)

Dreamgenics

NGS provider Spain

Dreamgenics is a biotech company that offers bioinformatics analysis services for genomic, transcriptomic and metagenomic NGS data using our Genome One software. Genome One (CE-IVD certified) is an advanced tool that allows the integration of all the bioinformatics solutions required for the study, including read alignment, variant calling and annotation. Our analyses identify high-quality genomic variants through high sensitivity and specificity standards, extracting important biological information and reducing validation costs. The services that we offer are the following: WGS, WES, Gene panels, Transcriptomics (RNA-Seq) and Metagenomics. Additionally, we hand in the results using our web viewer Genome One Reports (https://www.dreamgenics.com/en/genome-one/).

The use of our bioinformatics tools allows us to offer you high-quality results in a fast and simple way. By using our analysis services, you considerably reduce costs and the investment in technological devices, informatics and qualified professionals.

Lastly, we are an ISO 9001:2015, UNE-EN ISO 13485:2018 and UNE-ISO/IEC 27001:2017 certified company which represents our commitment to provide our customers with products and services that meet the most demanding quality standards.

Years in service: 12

Other services offered by Dreamgenics:

Service Description Price
Single Cell RNA-Seq Analysis We offer Single cell RNA-Seq bioinformatic analysis from FASTQ files including: - Sequencing and mapping quality control. - Alignment of reads against reference genome. - Quantification of gene expression at the single cell level. - Reduction of data dimensionality. - Clustering or division of cells into different groups and subgroups. - Differential gene expression analysis. - Study of the evol… $200.00 USD (per sample)
Differential Gene Expression Analysis Our RNA-Seq analysis includes: Quality control, Alignment, Quantification of gene expression, Differential gene expression analysis and Enrichment study of gene ontologies and pathways. It can also include the study of isoforms generated in alternative splicing events and the identification of other RNAs (smallRNAs and ncRNAs)*. We will deliver the results to the Genohub data bucket as well as t… $90.00 USD (per sample)
Exome Analysis Our bioinformatics analysis includes: Quality control, Alignment, Detection of high quality variants (SNVs, translocations and CNVs), Filtering of common variants, Annotation of variants obtained with multiple databases and prediction algorithms and Comparison between samples and extraction of recurrent variants. We will deliver the results to the Genohub data bucket as well as through our platf… $80.00 USD (per sample)
Transcriptome Annotation Our RNA-Seq analysis includes: Quality control, Alignment, Quantification of gene expression, Differential gene expression analysis and Enrichment study of gene ontologies and pathways. It can also include the study of isoforms generated in alternative splicing events and the identification of other RNAs (smallRNAs and ncRNAs)*. We will deliver the results to the Genohub data bucket as well as t… $90.00 USD (per sample)

RealSeq Biosciences Inc.

NGS provider United States of America

RealSeq Biosciences has an exceptionally fast turnaround time- typically one week. We are especially experienced in library construction from small RNAs. Small RNA libraries are prepared using our proprietary RealSeq® technology, the leader in bias reduction for small RNAs as shown by a core-facility comparison (ABRF). The starting input requirement for total RNA is as low as 1ng (RealSeq®-AC technology) or may be isolated from as little as 50ul of biofluid samples (RealSeq®-biofluids technology). We are experienced working with exosomes, plasma, serum, and whole blood samples. RealSeq Biosciences delivers fast and cost-effective mRNA sequencing services using either Nugen or NEB sequencing library preparation.

Years in service: 6

Other services offered by RealSeq Biosciences Inc.:

Service Description Price
Differential Gene Expression Analysis Reads processing and alignment. For each sequenced library: - Trimming of adapters - Alignment to the correspondent genome - We will provide raw files and processed (fastq and SAM files) mRNAs quantification - Align reads to reference transcriptome - We will provide mRNA reads counts (raw reads) Differential expression analysis (up to six groups) - Must have more than one sample 'per group' - S… $50.00 USD (per sample)
Differential Gene Expression Analysis Reads processing and alignment. For each sequenced library: - Trimming of adapters - Alignment to the correspondent genome - We will provide raw files and processed (fastq and SAM files) mRNAs quantification - Align reads to reference transcriptome - We will provide mRNA reads counts (raw reads) Differential expression analysis (up to six groups) - Must have more than one sample 'per group' - S… Inquire
Other Services Reads processing and alignment. For each sequenced library: - Trimming of adapters - Alignment to the correspondent genome - We will provide raw files and processed (fastq and SAM files) miRNAs quantification - Align reads to miRBase - We will provide miRNA reads counts (raw reads) Differential expression analysis (up to six groups) - Must have more than one sample 'per group' - Spreadsheet incl… Inquire
Other Services Reads processing and alignment. For each sequenced library: - Trimming of adapters - Alignment to the correspondent genome - We will provide raw files and processed (fastq and SAM files) miRNAs quantification - Align reads to miRBase - We will provide miRNA reads counts (raw reads) Differential expression analysis (up to six groups) - Must have more than one sample 'per group' - Spreadsheet incl… $50.00 USD (per sample)
Small RNA Annotation For organisms with a reference genome; or closely related species, we can run your FASTQ data through the miRdeep2 pipeline and give you the output files and a report that helps guide you in the organization of these files. Note, this is a freely available program and must be cited if used: (https://github.com/rajewsky-lab/mirdeep2) Cite: Marc R. Friedländer, Sebastian D. Mackowiak, Na Li, Wei Ch… $975.00 USD (flat price)

ChunLab

NGS provider South Korea

ChunLab specializes in NGS and bioinformatics for the fields of bacterial genomics, metagenomics, transcriptomics and bacterial identifications.

ChunLab maintains a portfolio of leading NGS technology to provide you a one-stop fully integrated NGS sequencing to bioinformatics solution.

While other companies deliver massive amounts of NGS data in Excel or text file formats, we go a step further to provide in-depth bioinformatics aligned with client's goal of discovery. Moreover, we provide sophisticated yet easy to use cloud-based tools, with our full-service solution, enabling quick visualizations, secondary analysis and comparative analysis.

Our user-friendly bioinformatics web tools are each tailored for a specific research need giving you true insight into your data without the aid of a bioinformatics specialist. Furthermore, by managing the entire pipeline, we ensure quality control at every step of the process meaning you have more meaningful downstream analysis.

Years in service: 14

Other services offered by ChunLab:

Service Description Price

genexa Ltd

Switzerland

genexa is a genomic data analysis provider located in Switzerland. Our bioinformatics services are centered around de novo assembly of genomes and metagenomes. We focus on processing, analysis, and interpretation of your genomics data. For all our fields of expertise, we offer to perform the entire analysis workflow from raw data to documentation, but also consulting and troubleshooting if required. genexa also provides resources to run computationally demanding tasks for specific jobs if you have an existing analysis workflow, but lack the computational resources to run it on large amounts of data. For further information check: genexa.ch

Years in service: 9

Other services offered by genexa Ltd:

Service Description Price
Differential Gene Expression Analysis Inquire
Comparative Genome Analysis Inquire
Custom scripting and special projects Inquire
Other Services We offer bioinformatics services using long-read sequencing (PacBio & Oxford Nanopore Technologies). We have several years of experience using third-gen. technologies, mainly applying these technologies for de novo assembly of individual genomes and metagenomes. We also offer transcriptomic analyses using long-read technologies. If you want to start using PacBio or Oxford Nanopore Technologies,… Inquire
Read Filtering and Cleaning Inquire
Metagenomic Analysis Inquire
SNP / Indel Calling Inquire
Genome Annotation Inquire
Transcriptome Annotation Inquire
Variant Annotation Inquire
Whole Genome de novo Assembly Inquire
Base Calling Inquire
Microbiome Analysis Inquire

Cofactor Genomics

NGS provider United States of America

Cofactor is focused on 3 main applications: RNA-sequencing, de novo assembly, and SNP/INDEL detection via resequencing. Over the last year, we have put significant R&D into our RNA-seq pipeline, and are now pleased to offer industry-leading protocols such as molecular spike-in controls, unprecedented QA/QC checks, ribosomal content screening, saturation analysis, and our ActiveSite Expression Viewer. These same protocols are also applied to our miRNA sequencing pipeline.

Other applications that fit well within our pipeline are: amplicon sequencing, custom capture and sequencing, 16S sequencing/microbiome sequencing, and highly custom projects.

Our scientists are happy to work with traditional model organisms, but we are experts in the more obscure. We've worked with nucleic acids from the complex field isolates, many plants including grapes, a variety of obscure animals including the Tardigrade (Water bear), and bacteria from multiple sources (micro biome, marine, biofuels, etc) to name a few.

While we are set-up to act as consultants, and support researchers throughout a full-service sequencing project, we are also happy to address the needs of more experienced researchers. Our expertise in library preparation or analysis may also be procured separate from the full-service offerings. And, those researchers who work with us in any capacity will have access to our team of scientists for support.

We have worked on small scale (1 sample) projects, all the way up through the larger, high throughput projects developed by big pharma. Every customer receives the same level of attentive, knowledgable customer service.

Years in service: 16

Other services offered by Cofactor Genomics:

Service Description Price

Genome Explorations

NGS provider United States of America

Genome Explorations, Inc. is a premier research institution providing global genomic profiling and molecular diagnostics services to academic centers, pharmaceutical and biotech industry, oncologists, and pathologists with innovative diagnostic, prognostic, predictive, and personalized testing.

Our ‘Complete Solution’ requires you, our client, to only provide us with your biological samples (DNA, RNA, Cells, Tissue or Blood). Our highly trained staff subsequently process these samples to completion and analyze them using the latest advanced bioinformatics solutions. This model, combined with the one-on-one interactions we have with our investigators, allows us to generate the highest quality data sets in the industry.

We believe that the combination of unparalleled quality diagnostics, industry-leading innovation, and exceptional service enable us to help a range of clients develop and implement a personalized approach to healthcare and, ultimately, eradicate the most malicious disease states.

Years in service: 9

Other services offered by Genome Explorations:

Service Description Price
Differential Gene Expression Analysis Inquire
Whole Genome de novo Assembly Inquire

Center for Bioinformatics and Functional Genomics

NGS provider United States of America

We are a genomics and bioinformatics core facility located within Miami University in Oxford, Ohio, USA. We have an Illumina MiSeq Benchtop Sequencer; an ONT Nanopore minION, an epMotion 5073m NGS Liquid Handling Workstation; an ABI 3130xl Capillary Electrophoresis analyzer (Sanger), a Promega Maxwell16, Agilent Bioanalyzer2100, Sage BluePippin, Covaris M220 ultrasonicator, Qubit 4, Nanodrop (Fluorospectrometer) 3300, BioRad CFX Connect, QuantStudio7, RotorGeneQ (qPCR), several high capacity bioinformatics workstations equipped with both CLC Genomics Workbench and BioBam OmicsBox software, as well as many OS/FOSS software packages.

We are thus able to start from source material and isolate high quality nucleic acid, and construct libraries and perform appropriate QC at each step. We can perform NGS on either the Illumina MiSeq or the ONT minION, as well as comprehensive post-run bioinformatics analyses.

Years in service: 10

Other services offered by Center for Bioinformatics and Functional Genomics:

Service Description Price
Differential Gene Expression Analysis Project turnaround is number of samples dependent. Analysis of DGE using CLC Genomics Workbench GLM. Output is rich figures, graphs, heatmaps, tracks. Metadata is require prior to analyses. All data exported as CLC format and CSV (generic spreadsheet). Full report also included. $32.00 USD (per hour)
Custom scripting and special projects Contact us about the possibility of a custom project/scripting for your problem. Inquire
Transcriptome de novo Assembly De novo transcription assembly; choose from an array of approaches/programmes - dependent on your needs and input data. $32.00 USD (per hour)
Transcriptome Annotation Full transcriptome annotation via NCBI BlastX nr database, PFAM, and KEGG Pathways mapping. $300.00 USD (flat price)
Microbiome Analysis 16S, 18S, ITS OTU analyses of amplicons - usually a 250 bp fragment size is used. SILVA, UNITE, MiDAS and Greengenes databases available. $32.00 USD (per hour)